THC A

Technically speaking, THCA (tetrahydrocannabinolic acid) is not a cannabinoid, but, as the name suggests, an acid—specifically, the chemical prototype of THC. It is the most abundant component in growing cannabis, the content of which can reach up to 15-30 percent of the total weight of the plant. It may sound surprising, but there is essentially no THC in untried, "live" cannabis. However, once it is harvested and begins to dry, the naturally occurring non-psychoactive THCA is gradually transformed into psychoactive THC. Exposure to heat can accelerate this process - smoking, vaporization, or cooking. From a chemical point of view, this is a reaction called decarboxylation, where THCA loses its carboxyl group and roughly 12 percent of its weight when converted to Delta 9 THC.
Overall, THCA is a THC analog, which is non-psychotropic and is found in the living cannabis plant's leaves. It is the most represented non-psychotropic cannabinoid that appears to be an agonist of TRPV receptors (which detects and regulates body temperature).
The extensive studies and clinical trials that have addressed the possible beneficial properties of THCA are very limited. But there are some hints that this cannabinoid might have anti-inflammatory and neuroprotective properties. In 2011 there was one study that investigated the interactions between CBD, CBDA, THC, THCA, CBG, and CBGA with the body's enzymes. These enzymes are important because they affect the production of prostaglandin, a lipid compound that is involved in inflammation. The results showed that all tested cannabinoids have anti-inflammatory effects. The neuroprotective properties of THCA were tested in a 2012 study conducted on an animal model, which was later published in the journal. This study examined the effect of THCA together with THC and CBD against neurotoxins, which are an organic chemical responsible for cell death. The researchers concluded their study by stating that - THC and THCA protect dopaminergic neurons.
THCA is a cannabinoid that can be found in plants of cannabis plants. It is an acidic, non-psychotropic compound. Once THCA is exposed to heat, it loses one carboxyl group and becomes Delta 9 THC, the cannabinoid that everyone associates with marijuana high. THCA does not seem to have any serious side effects in its acid form. However, THCA is unstable and naturally decarboxylates into the psychotropic cannabinoid THC.
Currently, there are not enough clinical studies and research that would deal in detail with which diseases THCA might be effective. However, laboratory experiments and patient testimonials indicate that the consumption of raw (non-carboxylated) cannabis has neuroprotective, anti-inflammatory, antispasmodic, antiemetic, and anticancer properties. According to anecdotal testimonies of patients, other therapeutic effects include, for example, the treatment of insomnia and digestive disorders.